Clinical application of endo-venous radiofrequency ablation combined with foam sclerotherapy in great saphenous varicose veins of the lower limbs

Abstract

Objective To investigate the clinical effect of endo-venous radiofrequency ablation combined with foam sclerotherapy in the treatment of great saphenous vein of varicose of the lower limbs. Methods The clinical data of 520 patients with primary saphenous varices admitted to Xuzhou Central Hospital from June 2016 to December 2018 were retrospectively analyzed, including 300 males and 220 females, aged 30-80 years with an average age of (60 ± 2) years. The study group included 260 patients(320 limbs) who underwent endo-venous radiofrequency ablation combined with foam sclerotherapy and compared them with 260 patients with saphenous varices who underwent conventional surgery. The operation time, intraoperative blood loss, postoperative activity out of bed days, hospitalization time, and the incidence of postoperative pain, saphenous nerve injury, wound infection, deep vein thrombosis, and hematoma were compared between the two groups. The postoperative quality of life, the closure of the saphenous vein in the 6th and 12th months after surgery, and the recurrence rate within 1 year were compared by follow-up. Results The operation time between the study group and the control group was (30.0±3.6) min vs. (60.4±5.9) min, intraoperative blood loss was (20.3±4.6) mL vs. (80.0±3.2) mL, postoperative activity out of bed days was (1.0±0.3)h vs.(6.3±2.0)h, hospitalization time was (2.0±0.8)d vs.(7.5±1.2)d, postoperative pain score was (3.2±0.3) vs.(5.4±1.2), saphenous nerve injury was 0 (0/260) vs. 2.3% (6/260), wound infection was 0 (0/260) vs. 3.0% (8/260), deep vein thrombosis rate was 0 (0/260) vs. 1.9% (5/260), the incidence of thigh hematoma was 0 (0/260) vs. 6.9% (18/260), and the quality of life score was (56.78±3.21) vs. (42.23±2.81); the difference between the two groups was statistically significant (P 0.05). Conclusion Radiofrequency ablation combined with foam sclerotherapy has a positive effect on primary saphenous vein varices, and it has good short-term and long-term effects, which can provide a better model for daytime surgery. Key words: Great saphenous vein; Foam sclerotherapy; Radiofrequency ablation; Daytime surgery