Abstract
Calcium hydroxide has a hard tissue inducing effect. It is a powder, that can be mixed with a physiological saline to a paste. The paste is highly alkaline with a pH 12.5 and its application to the pulp results in necrosis of the part of coronal pulp tissue shows no or only a milled inflammatory reaction. Analyzing the pH and the concentration of calcium ions in the periapical area, it is obvious that at least 2 weeks are necessary for calcium hydroxide bactericide activity. Calcium hydroxide retains its anti-bacterial properties for about two months when placed under a restoration, after which it degrades to calcium oxide and other less effective calcium salts. All calcium hydroxide preparations have a limited shelf life as they eventually turn into calcium oxide. Calcium hydroxide can be used as linings, for indirect and direct pulp cupping, root dressing, root canal sealant, apical closure. The vehicles play a supportive role, giving pastes chemical characteristics such as dissociation and diffusion as well as favoring the correct filling of the root canal which are decisive factors for antimicrobial potential and tissue healing. The mechanism of action of calcium hydroxide on tissues, inducing the deposition of mineralized tissue, is an extremely important aspect for the indication of calcium hydroxide, because it demonstrates biological compatibility of calcium hydroxide.
Highlights
Clinical Application of Calcium Hydroxide in Dental Pathology and EndodonticsAmela Laèeviæ1, Edina Vraniæ2, Irfan Zuliæ3* 1 Department of Dental Pathology and Endodontics, Faculty of Stomatology, Bolnièka 4, Bosnia and Herzegovina 2 Department of Pharmaceutical Technology, University of Sarajevo, Faculty of Pharmacy, È ekaluša 90, Bosnia and Herzegovina 3 Department of Pharmacology, Toxicology and Clinical Pharmacology, University of Sarajevo, Faculty of Medicine,
History of previous application shows a number of medicaments that have been used as pulp capping agents; gold, silver, different types of cements, antiseptic pastes, chemotherapeutics, ivory powder, dentin clips and calcium hydroxide [1]
The control of microorganisms by calcium hydroxide is determined by the liberation of hydroxyl ions, which requires an ideal length of time for effective microbial destruction [2,3]
Summary
Amela Laèeviæ1, Edina Vraniæ2, Irfan Zuliæ3* 1 Department of Dental Pathology and Endodontics, Faculty of Stomatology, Bolnièka 4, Bosnia and Herzegovina 2 Department of Pharmaceutical Technology, University of Sarajevo, Faculty of Pharmacy, È ekaluša 90, Bosnia and Herzegovina 3 Department of Pharmacology, Toxicology and Clinical Pharmacology, University of Sarajevo, Faculty of Medicine,
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