Clinical application and Fuzzy evaluation of autologous platelet-rich plasma mixed with fat graft in facial tissue depression

Abstract

Objective To evaluate the clinical effect of the facial soft tissue defect treated with platelet-rich plasma （PRP） mixed with purified fat. Methods 35 patients with facial soft tissue de- fects were treated by PRP mixed with centrifuged fat tissue. Using Fuzzy judgment method the clinical effectiveness of therapeutic outcomes were evaluated on fullness, injection of frequency and satisfaction during 3 to 6 months of follow-up. Results The therapeutic outcomes showed that the reconstructed face became a relative symmetrical and natural appearance with not evidently fat resorption and stable after operation, Both patients and surgeons were satisfied with the results. The score of effectiveness was highest in Fuzzy judgment. Conclusions The efficacy of PRP is significant in enhancing fat graft, reducing fat necrosis and resorption. The fat tissue mixed with PRP is a reliable reconstruction option for the facial soft tissue defect. Key words: Platelet-rich plasma; Fat grafting; Au＊ologous; Facial tissue defect; Fuzzy judgment