Abstract
Clinical and serological study on bluetongue virus serotype 4 in cattle in Albania
Highlights
Bluetongue is an infectious disease of ruminants, caused by Bluetongue virus (BTV), a member of the Reoviridae family, transmitted by certain insect species that serve as vectors [1,2,3,4]
The serum neutralization (SN) test confirmed the c-ELISA results revealing the presence of antibodies against BTV serotype 4 in 62.5% (80 samples) of competitive ELISA (cELISA) positive samples and the titer varies from 1:10 to 1:640
Majority of the clinically affected cattle were positive in cELISA and from nine serotypes known to be spread in Europe, only BTV serotype 4 was determine by serum neutralization test
Summary
Bluetongue is an infectious disease of ruminants, caused by Bluetongue virus (BTV), a member of the Reoviridae family, transmitted by certain insect species that serve as vectors [1,2,3,4]. BT disease (BTD) due by classical 24 serotypes is a non-contagious viral disease. The last serotypes are characterized by some addition features, causing asymptomatic infections, being directly transmitted, at least BTV-26 [8] having long viraemia Serotype 25 viral RNA was found for at least 2 years in individual animals, and the blood of some goats was infectious at 12-19 months [9]. Typical clinical signs of BTD occur when virulent BTV strains introduced into free areas by vectors or susceptible naive animals move to endemic areas [7]. Identification of BTV serotype is important for vaccination programs, BTD control and for BTV epidemiology studies. There are available advanced molecular methods, which offer several advantages compare to classical methods, classical method is valid, useful and is advised to use them in parallel with modern techniques
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