Abstract

Objective Femoral head osteonecrosis is a progressive clinical condition with significant morbidity and long-term disability. Several treatment modalities including both surgical and nonsurgical options have been used with variable levels of success. High-energy extracorporeal shock wave therapy is a nonoperative treatment option that has been described for early-stage disease. We aimed to assess the functional and radiological outcomes of extracorporeal shockwave therapy (ESWT) in the treatment of osteonecrosis of the femoral head (ONFH). Methods Thirty-three hips of 21 patients were included in this study. Adult patients with ONFH of any etiology and in the precollapse stage were included. Clinical (visual analogue scale [VAS] and Harris hip score [HHS]) and radiological (plain radiographs and magnetic resonance imaging [MRI]) evaluations were performed before and after intervention. We used 3000–4500 pulses in a single session performed under general anesthesia. Results At an average of 8 months after ESWT, pain scores and HHS were significantly improved compared with the preintervention scores (p<0.001). The overall clinical outcomes were improved in 21 hips (63.3%), unchanged in 5 hips (15.15%), and worsened in 7 hips (21.2%). A trend toward a decrease in the size of the ONFH was observed although not of clinical significance (p=0.235). MRI revealed significant resolution of bone marrow edema (p<0.003). Regression was observed in 9 lesions (42.9%) and progression in 1 lesion (4.7%); no change was observed in the remaining 23 lesions (52.4%). Conclusion ESWT is a viable noninvasive treatment option for early-stage ONFH. It significantly improves clinical outcomes and may halt or delay the radiographic progression of the disease in the precollapse stage.

Highlights

  • Osteonecrosis of the femoral head (ONFH) was originally described in 1925 as an ischemic necrosis of the hip area [1]

  • Such pathology is frequently observed in relatively young adults, and most of the untreated patients with ONFH progress to total hip arthroplasty (THA) with a collapse rate of 67% and 85% in asymptomatic and symptomatic patients, respectively [5]

  • Adult patients with ONFH due to any etiology in the precollapse stage, grades I or II according to the Association Research Circulation Osseous (ARCO) classification system, were included in this study

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Summary

Introduction

Osteonecrosis of the femoral head (ONFH) was originally described in 1925 as an ischemic necrosis of the hip area [1]. ONFH is a multifactorial disease with different etiologies ranging from genetic to idiopathic to certain risk factors such as trauma, hematological disorders, and steroid intake [4]. Such pathology is frequently observed in relatively young adults, and most of the untreated patients with ONFH progress to total hip arthroplasty (THA) with a collapse rate of 67% and 85% in asymptomatic and symptomatic patients, respectively [5]. High-energy extracorporeal shock wave therapy (ESWT) is a noninvasive procedure that has been successfully used for the last 20 years to manage various orthopedic conditions [6]. Multiple studies have demonstrated the therapeutic potential of ESWT in ONFH [7, 8]

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