Clinical and Radiographical Assessment of Topical Application of Collagen Fibrils on Tooth socket Healing

Abstract

Aims: To evaluate the effect of collagen fibers that placed immediately in alveolar bone socket after tooth extraction on homeostasis, quality and quantity of bone formation and their complications.Materials and Methods: The study group consists of 10 patients who attend to Oral and Maxillofacial Department in Dentistry College of Mosul University. The patients complained from chronic periapical lesions in badly carious two teeth in the same jaw (upper or lower jaw) that indicated for teeth extraction. Every patient underwent teeth extraction after receive local anesthesia with vasoconstriction, immediately after teeth extraction we put highly concentrated collagen material PARASORB® Dental Cones: 1 collagen cone contains 22.4 mg native equine collagen fibrils (RESORBA Wundversorgung GmbH & Co. KG, Germany) in one tooth socket (study site) and leave the other tooth socket to fill with blood clot (control group),Follow up the patients clinically and radiographically were done immediately after placement the material followed by different interval depending on the using test until six weeks. Results: The clinical assessment showed there is high significant difference (p-value ≤ 0.01) in the haemostatic condition between the study and control sites while there is no significant difference (p-value >0.05) in infection involvement of both study and control sites. The radiographical assessment of bone formation showed significant difference in bone density between study sites and control sites after two weeks (p-value ≤0.05), and high significant difference at fourth and sixth weeks (p-value ≤0.001). Conclusions: The collagen fibril play important role in control of hemorrhage following tooth extraction, prevent infection at the surgical site, promote granulation tissue formation and wound healing, reduce alveolar ridge resorption after tooth extraction (socket preservation) and enhance bone formation.