Abstract
Clinical and Radiographic Evaluation of Papilla Preservation Flap with or without Nanocrystalline Hydroxyapatite Bone Graft for Management of Periodontal Intrabony Defects: A Randomized Controlled Clinical Trial
Highlights
The main objective of periodontal therapy is to arrest progressive attachment loss through nonsurgical and surgical periodontal therapy [1]
The clinical and radiographic parameters recorded for papilla preservation flap (PPF) and PPF+nanocrystalline hydroxyapatite bone graft substitute (n-HA) groups throughout the study are shown in table 1
After 3 and 6 months, a significant improvement in probing pocket depth (PPD) and clinical attachment level (CAL) over baseline findings was observed in PPF and PPF+n-HA groups (P≤0.05) as well as from 3 to 6 months (P
Summary
The main objective of periodontal therapy is to arrest progressive attachment loss through nonsurgical and surgical periodontal therapy [1]. Obtaining true periodontal regeneration is considered by far the most elusive goal for treating periodontal intrabony defects. Variable techniques are used aiming for periodontal regeneration including bone replacement grafts [2, 3] that have been evaluated by previous studies and systematic reviewstoenhance regeneration of periodontal defects [4-7]. Bone replacement grafts provide structural scaffolds and matrices for blood clot development, maturation and osteoblasts proliferation [8]. Synthetic hydroxyapatite (HA) is an alloplastic material, chemically like the inorganic component of bone matrix which received great attention as a scaffold for bone tissue engineer¬ing. Theyhave shown no potential for enhancing new attachment formationacting primarily as inert biocompatible bone fillers [5, 7, 9]
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