Clinical and quality of life data correlation with a single-optic accommodating intraocular lens

Abstract

PurposeTo examine a single-optic accommodating intraocular lens (IOL) visual performance by correlating IOL implanted eyes’ defocus curve with the intraocular aberrometric profile and the impact on the quality of life (QOL). MethodsProspective consecutive case series study including a total of 25 eyes of 14 patients with ages ranging between 52 and 79 years old. All cases underwent cataract surgery with implantation of the single-optic accommodating IOL Crystalens HD (Bausch & Lomb). Distance and near visual acuity outcomes, intraocular aberrations, the defocus curve and QOL (NEI VFQ-25) were evaluated 3 months after surgery. ResultsA significant improvement in distance visual acuity was found postoperatively (p=0.02). Mean postoperative LogMAR uncorrected near visual acuity was 0.44±0.23 (20/30). 60% of eyes had a postoperative addition between 0 and 1.5diopters (D). The defocus curve showed an area of maximum visual acuity for the levels of defocus corresponding to distance and intermediate vision (−1 to +0.5D). Postoperative intermediate visual acuity correlated significantly some QOL indices (r≥0.51, p≤0.03; difficulty in going down steps or seeing how people react to things that patient says) as well as with J0 component of manifest cylinder. Postoperative distance-corrected near visual acuity correlated significantly with age (r=0.65, p<0.01). ConclusionsThis accommodating IOL seems to be able to restore the distance visual function as well as to provide an improvement in intermediate and near vision with a significant impact on patient's QOL, although limited by age and astigmatism. Future studies with larger sample sizes should confirm all these trends.