Clinical and psychosocial factors associated with seizure control in patients with juvenile myoclonic epilepsy

Abstract

To identify the clinical and psychosocial factors of a Colombian cohort of patients with juvenile myoclonic epilepsy and its relation to crisis control. Retrospective cohort study of patients over 14 years of age with a diagnosis of juvenile myoclonic epilepsy, with 12 months of follow-up in an epilepsy program, where the sociodemographic and clinical characteristics and the survey for the assessment of relapse conditioners. A bivariate and multivariate analysis was performed using binary logistic regression. Clinical records between November 2014 and December 2016 where 145 patients with a diagnosis of juvenile myoclonic epilepsy who met the selection criteria were evaluated. The factors associated with crisis control were: health plan, accessibility, personal attitudes, history of consumption, drug resistance, and crisis number per month; of these, health plans, personal attitudes, and crisis number per month persist with statistical significance after the logistic regression analysis. Psychosocial factors not only impact on crisis control, added to clinical factors explain 40% of crisis control in patients with juvenile myoclonic epilepsy and therefore affect their long-term prognosis.