Clinical and Psychosocial Characteristics of HIV-Positive and HIV-Negative Females with Opiate Dependence

Abstract

The objective of the study was to explore the clinical-psychological and social characteristics of injecting drugs women users (IDWU) with opiate dependence with different HIV status living on the territory of the Republic of Belarus based on multi-dimensional assessment of opiate dependence dynamics in order to develop therapeutic measures for relapse prevention and achievement of the long-term remission. Materials and methods: Totally 217 IDWU were examined. The research cohort was randomized into 2 groups: HIV-positive women (HPW) (104 persons, mean age 30.8 years (SD=4.86) and HIV-negative women (HNW) (113 persons, mean age 29.9 years (SD=6.67). The level of patients social functioning, quality of life, craving for narcotic substances were studied by means of the Scale of the social and functioning, SF-36 and the Scale of the craving for drugs. The particularities of the social functioning and life quality of women with opiate addiction and different HIV status were described. The results: show that the majority of IDWU were characterized by frequent work replacement and labor skipping (27/25.9% in HPW group vs 30/26.5% in HNW group; P>0.05). 21 /20.1% HPW vs 15/13.2% HNW (P<0.05) was characterized by low qualification, 43/43.3% HPW vs 41/36.2% HNW (P>0.05) - vocational education. HPW have more severely impaired psychosocial parameters compared to HNW. Family climate can be described as hostile aggressive (84/80.7% in HNW group vs 69/61.0% in HNW group; P<0.05). For women of both groups were characteristic parental alcohol abuse (18/17.3% in HPW vs 16/14.1% in HNW; P>0.05), and high level of parental divorces (24/23.1% in HPW vs 32/28.3% in HNW; P>0.05). It was found that the treatment itself allows to diminish the problems associated with drug use and HIV infection. Nevertheless, the short-term treatment course can only provide the clinical improvement but not stabilization of psychosomatic state of HIV-positive patients with opiate dependence. Conclusions: The results of the study indicates the vast majority of women who are injecting drug users, living in Belarus, can be characterized by high level of social functioning disturbances including domestic, social and professional relationship. They need for development of specific tactics of management to suit their needs, including the long-term complex treatment and rehabilitation programs.