Abstract
Objective To investigate the biological features and treatment of malignancies with multi-tumor factors in the pancreas and periampullary region. Methods A retrospective clinical analy-sis was conducted on 18 cases of the malignancies admitted to our hospital during 2005.1-2007.5. The clinical features, imaging findings, therapeutic and pathological data were analyzed. Meanwhile, the prognosis of this kind of malignancies was compared with that of adenoductal cancer undergoing radical pancreateetomy and that of periampullary carcinoma receiving palliative operation. Results The ma-lignancies were found in 11 men and 7 women with a mean age of 62.4±11.7 years. Tumors were lo-cated in the pancreas,the lower end of common bile duct and the ampullary part of duodenum in 14 ca-ses, ampullary duodenum and common bile duct in 1, pancreas and gallbladder in 1, pancreas and common bile duct in 1 and papillary duodenum and beginning of duodenum in 1. Fifteen of them re-ceived pancreaticoduodeneetomy (PD), 2 resection of distal pancreas plus splenectomy and the others total pancreatectomy. Ten patients died of tumor recurrence or liver metastasis several months after operation. For the 8 patients who survived, the longest survival time was 18 months. The median sur-vival time for those patients was only 13.2 months, which was significantly shorter than 27 months for the adenoductal cancer receiving PD and 20.9 months for the periampullary carcinoma undergoing pal-liative therapy. Conclusion The malignancies with multi-tumor factors in the pancreas and periampul-lary region are located mainly in the head of pancreas and the lower part of common bile duet, among which combination of IPMC or adenoductal carcinoma with other rare types of malignancies were the most common histotypes. The prognosis of this kind of carcinoma is poor and needs further research. Key words: Pancreatic neoplasms; Multi-tumor factors
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
