Abstract
T he antipseudomonal penicillins have proved to be useful components of antimicrobial therapy in episodes of infection in adults and children with malignancies. Addition of the beta-lactamase inhibitor clavulanic acid to ticarcillin promises to expand this usefulness. We evaluated the clinical efficacy, safety, and pharmacokinetits of ticarcillin disodium plus clavulanate potassium in episodes of presumed infection among adolescent patients with malignancies.
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