Abstract

Background and aim: Fascioliasis, which is caused by the large liver fluke species Fasciola hepatica and Fasciola gigantica, is arising and increasing and impacts on the health of people in endemic, specialy in Central and Highland regions of Viet Nam. This study is aimed at assessing the clinical, biological and ultrasound characteristics of human fascioliasis. Patients and methods: Between 12/2010 and 6/2012, study was carried out on 147 patients infected with fascioliasis at the clinic of IMPE Quy Nhơn. The clinical, biological and ultrasound characteristics were described. Results: the main clinical manifestations include: abdominal pain accounted for 100% including epigastric pain 84.4%), gastrointestinal disorders accounted for 92,5%, 100% of patients have positive reaction with Fasciola spp. antibody and 100% patients have hepatic lesion on ultrasound with size >30mm accounted on 95,2%. Patients with high eosinophil accounted for 63,9%. Fecal examination to find Fasciola spp. eggs only seen four cases. Conclusion: the clinical and paraclinical of human fascioliasis has remarkly changed compared with the medical literature.

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