Clinical and molecular predictors of mortality in neurofibromatosis 2: a UK national analysis of 1192 patients

Abstract

BackgroundNeurofibromatosis 2 (NF2) is an autosomal-dominant tumour predisposition syndrome characterised by bilateral vestibular schwannomas, considerable morbidity and reduced life expectancy. Although genotype–phenotype correlations are well established in NF2, little is...