Clinical and microbiological profile of urinary tract infection in children less than twelve years of the age and their antibiotics resistant pattern at a Tertiary Care Hospital in Kanpur, India

Abstract

Background: Urinary tract infection (UTI) is the most common bacterial infection which is seen in childhood population, which starts from the calyces of the kidney to the urethra. It is an important cause of morbidity and mortality in children mostly in the first 2 years of life. The Gram negative enteric bacilli, especially Escherichia coli and Klebsiella spp. the dominant pathogens. The objective of the study was to analyze the causative microorganism and their Antibiotic Resistance Pattern in UTI in childhood population between 0-12years of the age. Methods: This one year prospective and observational study was conducted in the Department of Microbiology; Rama Medical College Hospital & Research Centre Kanpur, Uttar Pradesh, India, on 100 pediatric patients (aged 0-12 years). All the pediatric age group (0-12 years) with suspected UTI and, whose urine culture showed one or two pathogen with colony counts greater than or equal to 105 colony forming units (CFU)/ml was included for the study. Clinical data was obtained from OPD and IPD Patients. Antimicrobial susceptibility was done for positive urine culture by Kirby-Bauer disk diffusion method. The data was expressed in terms of frequency and percentage.