Abstract

We have studied the cell population, neutrophil bactericidal activity, protein type and the content of human wound exudate which accumulates under an adhesive polyurethane film dressing (Op-Site ∗ ∗ Op-site (Registered Trade Mark): supplied by T. J. Smith & Nephew Ltd, Welwyn Garden City, Hertfordshire, England. ). The cell type and numbers of cells in the exudate are typical of an inflammatory response, and the protein content of the exudate is virtually indistinguishable from that of plasma. Also, the neutrophils present in the exudate killed Staphylococcus aureus at a rate similar to normal whole blood, indicating that there would be a minimal risk of clinical infection under Op-Site.

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