Abstract
Objective To investigate the clinical and laboratory characteristics of hematological malignancies with t(11;19)(q23;p13.1). Methods Chromosome specimens of bone marrow cell from a patient with hematological malignancy were collected. After short-term culture, and chromosome karyotype analysis was carried out by R banding technique. Results The chromosome karyotype of the patient diagnosed with AML M4c was t(11;19)(q23;p13.1). The patient did not obtain complete remission after application of MA regimen chemotherapy. Conclusions t(11;19)(q23;p13.1)translocation is a rare and recurring chromosome abnormality, which is related with a specific type of AML. The prognosis of the AML patients with this chromosome abnormality is poor. Key words: Chromosome; Translocation; Cytogenetics; Hematological malignancies
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
