Abstract
Violation of the kidney filtration function is common enough among patients with cardiovascular disease (CVD), especially against disorders of carbohydrate metabolism (IGM). Renal dysfunction (PD) is associated with more frequent development of cardiovascular complications. In turn, the probability of development of renal disease in patients with cardiovascular disease is significantly higher than in general population. This bidirectional pathogenetic mechanisms existing between cardiovascular and kidney diseases were the basis for the formation of cardiorenal syndrome concept. The review discusses the general parts of pathogenesis within the cardiovascular continuum. In addition, it shows the effect on metabolic disorders during CVD combined with renal dysfunction. The review reveals a recent view on the main mechanisms of cardiorenal syndrome.
Highlights
Cardiorenal Metabolic interactions are one of the most actual and discussed problems of modern medicine
Тhe basis for the formation of the concept of the cardiorenal continuum was high risk of complications in patients with comorbid pathology, two-way connections that exist between cardiovascular disease (CVD) and renal dysfunction (RD)
Results of scientific research have confirmed the correctness of the proposed concept, the mechanisms underlying the relationship between CVD, renal pathology, and diabetes mellitus have not been fully understood
Summary
Cardiorenal Metabolic interactions are one of the most actual and discussed problems of modern medicine. Тhe basis for the formation of the concept of the cardiorenal continuum was high risk of complications in patients with comorbid pathology, two-way connections that exist between cardiovascular disease (CVD) and RD
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