Abstract

D ESPITE intense and repeated antirejective therapy with triple combinations of cyclosporine A (CyA), cortisone (CORT), antithymocyte globuline (ATG), and consecutive monoclonal CD3 antibodies (OKT3) in acute rejection episodes, still confront transplant recipients who have relapses of acute rejection (AR). In a patient subset after allogenic TX we asked (1). Can this recipient group be characterized by risk factors? and (2) Is there an efficacious regimen for safe therapy of recurrent rejection episodes?

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