Clinical and histological findings of a typical case of angiolymphoid hyperplasia without eosinophilia: a rare and difficult-to-treat disease

Ivonne Dannesy Rodriguez Hernandez

doi:10.7241/ourd.20193.13

Abstract

Clinical and histological findings of a typical case of angiolymphoid hyperplasia without eosinophilia: a rare and difficult-to-treat disease

Highlights

Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare, locally proliferative, benign and idiopathic condition that usually affects middle-aged Caucasian women [1]
We report a case of a patient diagnosed with ALHE, without eosinophilia, with good clinical response to topical corticosteroid treatment
A cutaneous lesion biopsy was performed in the lesion on the left tragus and submitted to histopathological examination, which revealed diffuse inflammatory infiltrate with lymphocytes and eosinophils, hyperplasia of the blood vessels and capillaries with prominent endothelium, confirming the diagnosis of Angiolymphoid Hyperplasia with Eosinophilia (Fig. 2)

Summary

Introduction

Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare, locally proliferative, benign and idiopathic condition that usually affects middle-aged Caucasian women [1]. ALHE and Kimura’s disease were considered for many years the same entity and to this day they are often confused. Both diseases share common clinical and histopathological features. It is believed that they are two distinct diseases because of their clinical and histopathology differences [4].

Results

Conclusion