Abstract
True fibroma is a rare neoplasm in the oral cavity; it is a benign proliferative lesion of the connective tissue. Its clinical features include nodules firm to soft, hyperkeratinized or ulcerated surface, and pinkish-whitish color. It presents histologic differential diagnosis with pyogenic granuloma, giant cell peripheral granuloma, and peripheral ossifying fibroma. We describe a case report of a 75-year-old female patient, who presented rounded lesion of 1 cm, with smooth, homogeneous, and non-painful surface, firm consistency, which evolved for 3 years after the exchange of removable prosthesis. The patient reported that frequency of biting in the right cheek became constant after the new prosthesis. Through excisional biopsy, histopathological examination confirmed the absence of malignancy and the presence of fragments of benign mesenchymal neoplasia. Such neoplasia consisted of mature fusiform cells, compatible with fibroblasts in a matrix of mature fibrous tissue and with hyperkeratinized epithelial tissue presenting cellular edema.
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