Clinical and genetic analysis of a familial nonsyndromic oligodontia in a female patient: A rare case report

Abstract

Teeth agenesis is the most prevalent craniofacial congenital malformation in humans. Missing teeth is described in literature by various terms such as oligodontia, anodontia, and hypodontia. While tooth agenesis may be associated with several syndromes, nonsyndromic oligodontia refers to the congenital absence of more than six teeth in the absence of any other deformity. Studies in molecular genetics have made it possible to identify the exact genes responsible for the development of teeth and trace the mutations that cause oligodontia. The present case describes agenesis of permanent teeth which are familial and with no apparent systemic abnormalities.