Clinical and Forensic Applications of Capillary Electrophoresis

Abstract

Section I. Introduction Capillary Electrophoresis: General Overview and Applications in the Clinical Laboratory Manjiri Lele, Subodh M. Lele, John R. Petersen, and Amin A. Mohammad Basic Principles and Modes of Capillary Electrophoresis Harry Whatley Section II. Protein Electrophoresis Capillary Coatings for Protein Analysis Kannan Srinivasan, Chris Pohl, and Nebojsa Avdalovic Clinical Serum Protein Capillary Zone Electrophoresis Carl R. Jolliff Serum and Urine Paraprotein Capillary Electrophoresis Carl R. Jolliff Cerebrospinal Fluid Protein Electrophoresis John R. Petersen and Amin A. Mohammad Lipoprotein Analysis Rainer Lehmann Clinical Analysis of Structural Hemoglobin Variants and Hb A1c by Capillary Isoelectric Focusing James M. Hempe, Alfonso Vargas, and Randall D. Craver Section III. Metabolic Diseases Amino Acid Analysis, Mary Kathryn Linde. Organic Acids Kern L. Nuttall and Norberto A. Guzman Steroids, Cecilla Youh Amin A. Mohammad, and John R. Petersen Section IV. Immunoassay Capillary Electrophoresis Based Immunoassay Bode Adesoji, Amin A. Mohammad, and John R. Petersen Section V. Molecular Diagnostics Quantitation of Viral Load Jill M. Kolesar The Application of Capillary Electrophoresis in the Analysis of PCR Products used in Forensic DNA Typing Bruce R. McCord and John M. Butler Capillary Electrophoresis with Electrospray Ionization Mass Spectrometry Samir Cherkaoui Section VI. Mass Spectrometry, Therapeutic Drug Monitoring, and Toxicology Capillary Electrophoresis-Mass Spectrometry of Biologically Active Peptides and Proteins Stephen Naylor and Andy J. Tomlinson Serum Drug Monitoring by Capillary Electrophoresis Zack K. Shihabi Applications of Capillary Zone Electrophoresis in the Analysis of Metal Ions of Clinical Significance Lokinendi V. Rao, John R. Petersen, Amin A. Mohammad, and Anthony O. Okorodudu Clinical and Forensic Drug Toxicology: Analysis of Illicit and Abused Drugs in Urine by Capillary Electrophoresis Wolfgang Thormann and Jitka Caslavska Screening Biological Specimens for Drugs of Forensic Significance John C. Hudson, Murray J. Malcolm, and Mauro Golin