Abstract
Summary:The review covers the findings of the epidemiological trial on urinary tract infections (UTI) incidence, acute and chronic pyelonephritis in children of Primorsky territory. The significant impact of environmental climatic and heliogeophysical risk factors on pyelonephritis morbidity in children was detected. The most significant factors of UTI development in Primorsky territory were defined. Clinical and laboratory features of this pathology in children at the present day are represented. The ideas of pathogenesis of bacterial inflammation in urinary tract have been broaden. The role of tumor necrosis factor-alpha and its type 2 soluble receptor in persistence and in progression of the inflammation process, which can lead to non-reversible sclerotic changes in kidney tissue, was determined. The role of nitrogen oxide in pathogenetic mechanisms of renal hypertension in children was determined. The complex rehabilitation of patients with local mineral water was considered. The obtained data can be used in further researches, in the work of children›s medical institutions of cities and regions of Primorsky territory.
Highlights
The review covers the findings of the epidemiological trial on urinary tract infections
which can lead to non-reversible sclerotic changes in kidney tissue
The obtained data can be used in further researches
Summary
Частота заболеваний органов мочевой системы среди детей в Приморском крае составляет 26,2 на 1000 соответствующего населения в год [4]. [6], распространенность ИМВП среди детей Приморского края составила 28,8 на 1000 детского населения, что выше среднероссийского показателя. Установлено и достоверное влияние на заболеваемость ИМВП среди детей и подростков экзогенных факторов: при низких температурах и воздействии электромагнитного излучения Солнца с частотой 245, 410 и 606 МГц фиксируется увеличение случаев микробно-воспалительных заболеваний почек, причем развитие клинических симптомов имеет отсроченный характер от момента воздействия природных факторов – в среднем на 2–3 месяца.
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