CLINICAL AND EPIDEMIOLOGICAL FEATURES OF THE BRUCELLOSIS IN CHILDREN OF THE STAVROPOL TERRITORY

Abstract

Objective: to study the clinical and epidemiological features of brucellosis in children in the Stavropol region. Materials and methods: Analysis of brucellosis is made and the share of brucellosis in the Stavropol Territory from 2010 to 2014 is clarified. The paper used the data from the Territorial Rospotrebnadzor in the Stavropol Territory. Dynamic clinical indices were analyzed in 17 children with brucellosis under treatment and dispensary observation in the State Budget Institution of Health of the Stavropol Territory «Regional Clinical Hospital of Infectious Diseases». Analyzed an outbreak of brucellosis in Essentuki in 2016. We used the following methods: bibliographic, monographic description, epidemiological, analytical, statistical methods. Results. The proportion of the incidence of brucellosis in children in Stavropol Krai in comparison with the Russian figures were: in 2010 – 8,33%, in 2016 – 56%. A household way of infection increases, including children, who were infected in the farms of their own parents. The age of infection was 12–16 (47,06%), 8–11 (35,29%) and 4–7 years (17,65%). The main clinical syndromes were: arthritic, vegetative, asthenic, lymphoproliferative syndrome, liver disease, splenomegaly. Isolated forms did not occur. Predominantly, large joints with dysfunction of joints of I–II degree were affected. Late referral after the initial manifestation is typical. Late initiation of treatment. The etiotropic therapy is carried out at least 4 weeks, in the presence of carditis – up to 16 weeks. Conclusion. The epidemiological situation of brucellosis in the Stavropol territory has been tense in the recent years. The active migration of the population from the regions of the North Caucasus Federal District contributes to this. Intensive incidence rate of brucellosis exceeds the average Russian level by 5–8 times each year. The combination of the locomotor and visceral forms prevailed in the clinical picture. In dynamics, within 2–7 years persistent asthenovegetative and arthritic changes were formed and frequent exacerbation of bacterial flora and ENT pathology of the gastrointestinal tract was observed.