Abstract

AbstractGBS neonatal infection in Japan is on the trend of increase, which was confirmed by bibliographic analysis of data on neonatal bacterial infection in the past two decades and by recent clinical data. Vaginal GBS carrier rate of pregnant women in Japan was 11.3%, which was regarded as compatible with those from western countries. By analysing clinical cases, we proposed to classify GBS neonatal systemic infection as follows; amniotic infection type, rapid progress sepsis type and slow progress meningitis type, instead of early onset and late onset types. Serotypes la and III were predominant in clinical cases, especially after 24 hours of life, while Ic and III were the most frequent serotypes discovered from maternal vagina.

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