Abstract
Today in the world there is a high prevalence of asthma, and the mild severity occupies a leading position in the structure of morbidity. A mild asthma is a pathology that, with a prolonged asymptomatic course, can lead to severe exacerbations, and even death. Despite this, at present there are difficulties leading to an insufficient and untimely diagnosis of asthma, as a result of which exacerbations are often recorded in patients with a mild severity of the disease. The literature review examined the clinical features of mild asthma, as well as the modern principles of treatment of patients with mild disease severity. In addition, a review of recent studies aimed at studying morphological and pathophysiological changes in mild asthma is presented. Mild asthma, as a rule, is stable, but sometimes it can spontaneously develop into extremely severe, and the causes of such changes remain unclear. The analysis of the studies revealed endogenous and exogenous factors that affect the induction of bronchial asthma and exacerbate its course. It is also important that bronchial obstruction, apparently, appears from the first years of life and persists in the future, in connection with which it is important to understand the value of diagnosis measures and the effectiveness of interventions in the early stages of bronchial obstruction to prevent disease progression. In this regard, the problems of early diagnosis of mild asthma and the timely appointment of appropriate therapy remain today important and relevant.
Highlights
It is important that bronchial obstruction, apparently, appears from the first years of life and persists in the future, in connection with which it is important to understand the value of diagnosis measures and the effectiveness of interventions in the early stages of bronchial obstruction to prevent disease progression
Immediate bronchodilator response in FEV1 as a diagnostic criterion for adult asthma // Eur. Respir
Summary
На сегодняшний день в мире наблюдается высокая распространенность бронхиальной астмы (БА), а легкое течение болезни занимает лидирующие позиции в структуре заболеваемости. Легкая форма астмы является патологией, которая при длительном бессимптомном течении может привести к тяжелым обострениям, и даже к летальному исходу. В литературном обзоре рассмотрены клинические особенности БА легкого течения, а так же современные принципы терапии пациентов с легкой степенью тяжести заболевания. Кроме того в работе представлен обзор последних исследований, направленных на изучение морфофункциональных и патофизиологических изменений при БА легкого течения. В связи с этим проблемы ранней диагностики БА легкого течения и своевременного назначения соответствующей терапии остаются на сегодняшний день важными и актуальными. Ключевые слова: легкая бронхиальная астма, терапия легкой астмы, диагностика, обструкция дыхательных путей, респираторные симптомы
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