Abstract
This article shows clinical features of the course of hypoxic-ischemic encephalopathy (HIE) in premature infants depending on gestation age. It has been shown that the brain and lungs suffer the most, which contributes to the development of neurological and somatic disorders. Studies have shown that the clinical course of HIE in premature infants is directly dependent on the state of health of mothers, fetoplacental background, on the structural and functional immaturity of the brain of infants, the presence of ante-, intra- and postnatal factors. The smaller the gestational age of the child, the more severe the long-term consequences from the central nervous system. The most severe course of HIE was observed in children with extremely low birth weight (ELBW) and low birth weight of (LBW).
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