Abstract
Objective: to study clinical, anamnestic, and laboratory parameters in children with acute and chronic urticaria.Materials and methods: fifty-five children were examined who were admitted to the pediatric department and day-time inpatient facility of the State Children’s Clinical Hospital No. 17 in Ufa in 2019. Two groups were formed: 44 patients with acute urticaria (Group 1) and 11 patients with chronic urticaria (Group 2). For the correct analysis of the hemogram and immunogram, 2 subgroups of patients with acute urticaria were formed: Group 1a – 13 children under 5 years old and Group 1b – 31 children over 5 years old.Results: acute urticaria was typical for young children (Z cor. = -2.14665; p = 0.031822). In children with acute urticaria under five years of age, there was a correlation (p < 0.05) of age with low serum JgA levels (rs = 0.806380) and the incidence of gastropathology with JgM levels (rs = 0.872872); JgG (rs = 0.763763) and the number of blood leukocytes (rs = 0.692820). In children with acute urticaria over five years of age, a correlation was found between age and concomitant gastropathology (rs = 0.421569). Patients with chronic urticaria are characterized by eosinophilia (Z cor. = -2.96741; p = 0.003003) and a pathogenetically significant increase in the CEC level (Z cor. = 1.98537; p = 0.047104).Conclusion: the revealed differences should be taken into account during the examination and management of children with urticaria.
Highlights
Objective: to study clinical, anamnestic, and laboratory parameters in children with acute and chronic urticaria
Results: acute urticaria was typical for young children (Z cor. = -2.14665; p = 0.031822)
In children with acute urticaria over five years of age, a correlation was found between age and concomitant gastropathology
Summary
Клинико-анамнестические и лабораторные характеристики детей с острой и хронической крапивницами. Цель: изучение клинико-анамнестических и лабораторные показатели у детей с острой и хронической крапивницей. Для корректного анализа гемограммы и иммунограммы сформированы две подгруппы пациентов с острой крапивницей: Iа — 13 детей до 5 лет, IIб — 31 ребенок старше 5 лет. У детей с острой крапивницей младше пяти лет была выявлена корреляционная связь (p < 0,05) возраста с низким уровнем JgA в сыворотке крови (rs = 0,806380) и частота гастропатологии с уровнем JgМ (rs = 0,872872); JgG (rs = 0,763763) и количеством лейкоцитов крови (rs = 0,692820). У детей с острой крапивницей старше пяти лет выявлена корреляционная связь возраста с сопутствующей гастропатологией (rs = 0,421569). Clinical and anamnestic differences between acute and chronic urticaria in children. Objective: to study clinical, anamnestic, and laboratory parameters in children with acute and chronic urticaria. Conclusion: the revealed differences should be taken into account during the examination and management of children with urticaria
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