Clinical analysis ofsquamous cell carcinoma of renal pelvis

Abstract

：Objective To review thediagnosis and treatment of squamous cell carcinoma of renal pelvis. Methods The clinicaldata from October 1991 to May 2009 of eight cases of squamous cell carcinoma of renalpelvis were reviewed and analyzed retrospectively. The symptoms of the patients werehematuria (eight cases), pain (seven cases) and abdominal mass (one case). All patientsunderwent B-ultrasound and IVU examination and four cases underwent CT scan. Three caseswere diagnosed as having a tumor before surgery. Five cases were diagnosed as renalcalculus, two of the five cases were diagnosed by intraoperative frozen section. Radicalnephroureterectomy were performed in four cases, nephrectomy in three cases and palliativeresection in one case. Results Histological classification revealed that six cases weremoderately differentiated, one case was well differentiated and one case was poorlydifferentiated. Two cases had stage pT1/pT2 and six cases had stage pT3/pT4. 2 cases hadregional lymph nodes metastasis. Seven cases were followed-up. All patients died of tumorrecurrence or metastasis. The median tumor specific survive time was six months (rangefrom two months to 42 months). Conclusions Squamous cell carcinoma of renal pelvis isoften occurs concurrently with urolithiasis which could lead to difficulty in diagnosebefore operation. As the most of the patients were diagnosed with advanced stage disease,squamous cell carcinoma of renal pelvis tended to early recurrence and metastasis and theprognosis was very poor.