Clinical analysis of the first case with imported Zika virus disease in China

Abstract

Objective To understand the epidemiological characteristics and clinical features of Zika virus disease, and to improve its prophylaxis and treatment. Methods The first case with imported Zika virus disease in China was retrospectively reported and analyzed. The literature of Zika virus infection in human was reviewed. Results This patient was the first case with imported Zika virus disease in China who presented with typical clinical characteristics and had clear epidemiological history. All the contacts were test negative for Zika virus nucleic acid. Literature retrieval showed evidence of Zika virus propagation in more than 40 countries in Africa, Asia, and Americas. The majority of patients presented with mild symptoms and the main prevention measures included mosquito control and improved awareness of personal protection. Conclusions Human infected with Zika virus often shows recessive infection. Only a small part develop disease and have generally good prognosis with supportive treatment. Key words: Zika virus; Import; Clinic manifestation; China