Clinical analysis of risk factors for postoperative anastomotic leakage in geriatric patients with esophageal carcinoma

Abstract

Objective To investigate the risk factors for postoperative anastomotic leakage in geriatric patients with esophageal carcinoma and provide new insights into clinical prevention and treatment. Method The fifty-six patients with anastomotic fistula were chosen from 636 esophageal carcinoma patients who underwent esophagectomy in Department of Thoracic Surgery from January 2011 to January 2016.In the 56 patients, the ratio of male (39 cases) to female (17 cases) was 2.3∶ 1.0, with the age range of 60 - 81 years, average of (66.4±8.6) years. The retrospective analysis was performed for obtaining the risk factors for anastomotic leakage. Results Fifty six cases who suffered from anastomotic fistula showed 10 cases (17.9%)with hormone administration, 17 cases (30.4%) with preoperative chemo-radiotherapy, 32 cases (57.1%) with the basic diseases, 27 (48.2%) with preoperative dystrophia. In addition to the old age and tumor, the other risk factors for anastomotic leakage included the hormone use, preoperative malnutrition, and preoperative chemo-radiotherapy. Conclusion High attentions have to be paid to the prevention and treatment of anastomotic fistula patients with chronic diseases, hormone use, preoperative malnutrition and preoperative chemo-radiotherapy. Key words: Esophageal neoplasms; Esophageal fistula; Risk factors