Clinical analysis of primary small intestinal non-hodgkin lymphoma

Abstract

Objective To explore the clinical characteristic,diagnosis and treatment regimens of primary small intestinal non-Hodgkin lymphoma.Methods Data of 58 small intestinal non-Hodgkin lymphoma patients treated from January,1999 to December,2009 was collected and analyzed.Results Abdominal pain is the common symptom of primary small intestinal non-Hodgkin lymphoma.All the patients were stage I and stage Ⅱ.The distal ileum and ileocecal junction are the most predilection site.The overall 5-year survival rate is 52.8%,and it is 62.5% and 46.7% for I-stage and Ⅱ-stage patients respectively with significant statistics difference(P=0.023). The 5-year survival is 27.2% for patients receiving operation alone,and 58.6%for patients receiving operation plus chemotherapy and or radiotherapy,which has significant statistics difference(P=0.004).Conclusions Treatment of primary small intestinal non-Hodgkin lymphoma should prefer the therapy based on surgery with combination of chemotherapy and radiotherapy. Key words: Non-Hodgkin lymphoma,intestinal; Surgical operation; Radiotherapy; Chemotherapy