Clinical analysis of PASCAL laser and Krypton ion laser treatment of diabetic retinopathy

Abstract

Objective To evaluate the clinical efficacy difference of PASCAL laser and krypton ion laser treatment of diabetic retinopathy.Methods From June 2010 to June 2012 in The Eye hospital of Tangshan,200 cases (378 eyes) of pre-diabetic proliferative retinopathy and 200 cases (296 eyes) of proliferative diabetic retinopathy were randomly divided into PASCAL laser treatment groups and krypton ion laser treatment group.FFA,vision correction,and comfort questionnaire were re-examined three months after treatment.Results There were similar efficacy on promote avascular area subsided in patients with pre-proliferative diabetic retinopathy both using PASCAL laser and krypton ion laser treatment,the difference was not statistically significant.However,visual impairment was significantly less by PASCAL laser than krypton ion laser treatment (x2 27.562a,P 0.000,P ＜0.01),patients tolerated PASCAL laser significantly better than krypton ion laser (x21.940Ea,P 0.000,P ＜0.01),the above differences were statistically significant.The promoting neovascular regression role of PASCAL laser was weaker than krypton ion laser in the treatment of patients with proliferative diabetic retinopathy (x2-7.562a,P 0.000,P ＜0.01).PASCAL laser on visual impairment was significantly less than krypton ion laser (x2 13.408a,P 0.000,P ＜0.01),patients tolerated PASCAL laser significantly better than krypton ion laser (x2 1.025Ea,P 0.000,P ＜0.01),the above differences were statistically significant.Conclusions PASCAL laser compared with krypton ion laser treatment has some advantages in the early proliferative diabetic retinopathy,while the poor results in the treatment of proliferative diabetic retinopathy. Key words: PASCAL laser; Krypton ion laser; Diabetic retinopathy