Clinical Analysis of Lactating Adenoma and Related Literatures Review

Abstract

Objective To investigate the etiology, clinical manifestations and treatment methods of lactating adenoma. Methods A total of 11 cases with lactating adenoma were included into this study. Among them, five cases were diagnosed as lactating adenoma in the Center for Prevention and Cure of Breast Disease, Beijing Haidian Maternal and Child Health Hospital From July 1,2004 to March 30,2012, another 6 cases of lactating adenoma were searched from Pubmed and Wanfang Database from July 20th, 1998 to June 21th, 2012. This research followed the process conforms to the mammary gland disease prevention and control center of Beijing Haidian District Maternity and Child Care ethics standards promulgated by the human subjects committee. Results Among those 5 cases, one case found breast lumps at gestational age of 17 weeks and underwent breast surgery for neoplasms at gestational age of 25 weeks. Postoperative histopathological examination results showed secrete breast tumor. Two patients underwent breast formed sinus tract and resected. One case was puctured 4 times guiding by the color Doppler ultra sound. After the infection was controlled, breast neoplasm was cutted off. One case was found breast neoplasm during the process of regular breast abscess drainage and underwent resection. The follow-up showed no one had recurrence. Among those 6 cases, three patients reported in literatures abroad showed patients accepted surgery during pregnancy, and another three patients reported in literatures in domestic showed patients underwent postpartum surgery treatment. And five cases underwent neoplasm resection and one case who was combined with breast cancer underwent breast cancer modified radical. No recurrence were found among those six patients. Conclusions Lactating adenoma is a rare benign tumor during perinatal period. Excessive intervention such as massage could lead to infection. Infections after maturation can be treated by the incision and drainage, or fine needle aspiration and flush with ultrasound-guided. Key words: Lactating adenoma; Cause; Infection