Clinical analysis of interstitial lung disease associated with lung cancer

Abstract

Objective To investigate the clinical features of interstitial lung disease associated with lung cancer.Methods The clinical manifestations,chest radiography,and pathology of eight interstitial lung disease associated with lung cancer patients were analyzed.All cases were followed up after treatment.Results The patients included six males and two females,six cases had history of smoking,three cases had positive immunological markers.The main clinical symptoms were hemoptysis,dry cough,frothy sputum,and shortness of breath.The pathological types of interstitial lung disease were usual interstitial pneumonia and nonspecific interstitial pneumonia.The pathological type of lung cancer was mainly adenocarcinoma.Five cases were treated with radical resection,three cases of them were unable to tolerate postoperative chemotherapy,two cases of them were given adjuvant chemotherapy.One case was died of severe bone marrow suppression after chemotherapy.The other two cases abandoned further treatment and died at eight months and ten months after diagnosis,respectively.Conclusions Interstitial lung disease associated with lung cancer is usually occult in onset and should be paid attention. Key words: Interstitial lung disease; Lung cancer ; Clincal manifestations ; Misdiagnosis