Abstract
Objective To analyze the clinical effect of gamma globulin combined with aspirin in the treatment of children with Kawasaki disease. Methods Fifty children with Kawasaki disease treated in Liaocheng People’s Hospital from March 2017 to October 2018 were randomly collected. The children were divided into control group and observation group, with 25 cases in each group. The control group was treated with routine dose of aspirin and the observation group with high dose of aspirin. Results The clinical effective rate in the observation group was higher than that in the control group, and the incidence of cardiovascular complications was lower than that in the control group, and the difference was statistically significant (P< 0.05). The main symptoms such as fever, lymphadenopathy, mucosal congestion, hand and foot swelling and other main symptoms disappeared and hospitalization time were significantly shorter than those in the control group (P< 0. 05). After treatment, the CRP, WBC, PLT of the children in the observation group was significantly shorter than that in the control group (P< 0.05). The level of PCT was significantly lower than those of control group (P< 0.05). Conclusions The effect of gamma globulin (high dose) plus aspirin in the treatment of children with Kawasaki disease is reliable.It has good safety and generlized value. Key words: Kawasaki disease; Aspirin; Gamma globulin
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