Clinical analysis of eccentric occluder in interventional closure treatment for intracristal ventricular septal defects

Abstract

Objective To investigate the clinical application of eccentric occluder in the treatment of intracristal ventricular septal defects (VSD) and its complications as well as to summarize the experience of interventional therapy on intracristal VSD in order to provide the basis for the selection of surgical indications in the future practices. Methods The clinical data of 65 patients with intracristal ventricular septal defects underwent interventional treatment in the Heart Center of the Affiliated Children's Hospital of Nanjing Medical University from January 2009 to February 2015 were retrospectively analyzed. All the patients were divided into two groups according to the size of the occluder: Group A (the size of occluder ≤6 mm, n=29) and Group B (the size of occluder ≥7 mm, n=36). Then the relevant data related to the treatment of the 2 groups was analyzed and compared. Results The number of patients complicated with pulmonary hypertension before surgery and major complications after surgery, operation time, X-ray exposure time of the group A and group B was 0 vs. 7, 1 vs.10, (62.4±13.8) min vs. (84.1±16.7) min, (13.2±5.6 )min vs. (20.5±7.4) min, respectively, showing significant difference (all P values 0.05). Conclusions With the diameter of intracristal VSD increasing, the size of the occluder employed in the operation is enlarged, and as this is true of the difficulty and risk of operation and postoperative complications. Therefore, it should be more cautious in the treatment of intracristal ventricular septal defects in patients who undergo the interventional therapy with eccentric occluder ≥7 mm. Key words: Heart septal defects, ventricular; Septal occluder devices; Interventional therapy; Complication