Abstract
Objective To evaluate the clinical curative effect of amniotic membrane grafting for ocular chemical burn and thermal burn.Methods We collected 28 patients (36 eyes) with ocular chemical and thermal burn,which had been treated with amniotic membrane grafting in our hospital.The follow-up time ranged from 6 months to 24 months.The postoperative visual acuity,the condition of amniotic membrane transplant,renovation of cornea,healing time of corneal epithelium and complications were observed.Results Postoperative corrected visual acuity was improved in 24 eyes(66.7％),it was not changed in 9 eyes(25.0％),the visual acuity declined in 3 eyes(8.3％).The amniotic membrane survived in 29 eyes and the survival rate was up to 80.6％.The cornea of 3 eyes recovered to transparent.Nebula emerged in 12 eyes eventually.Corneal macula emerged in 14 eyes.5 eyes ended up with leukoma.2 eyes resulted in cornea perforation.The corneal epithelium of 34 eyes recovered entirely within 1 to 4 weeks.2 eyes failed after therapy.Conclusion Amniotic membrane grafting is an effective method to deal with ocular surface burn.But for severe burned eyes,several times of amniotic membrane transplantation need to be done for preserving eyeball. Key words: Eye burns; Reconstruction,ocular surface; Amniotic membrane; Transplantation
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