Abstract

Objective To analyze the types of strabismus and the path of the genetic features in binocular diplopia in adults in order to improve the therapeutic effect of treatment.Methods A Hess screen,red glass test and motility examination were used to evaluate ocular alignment,ocular ductions and versions and diplopic image analysis in 117 cases of binocular diplopia.Biochemical examination of blood,image analysis (MRI and/or MRA) and an edrophonium test were used.Results The main types of strabismus among the 117 cases were paralytic strabismus that included sixth cranial nerve palsy (35 cases,29.9％),third cranial nerve palsy (28 cases,23.93％),superior oblique palsy (19 cases,16.2％),and multiple cranial nerve palsy (8 cases,6.8％).Restricted strabismus included restricted hypotropia (18 cases,15.4％) and restricted exotropia (2 cases,1.7％).Concommitent strabismus included early onset intermittent exotropia (4 cases,3.4％)and acute esotropia (4 cases,3.4％).The main causes were diabetes (32 cases,27.4％),vascular disease (20 cases,17.1％),trauma (15 cases,12.8％),brain tumor (11 cases,9.4％),virus infection (10 cases,8.6％),Graves disease (9 cases,7.7％),myasthenia gravis(5 cases,4.3％),chemotherapy (2 cases,1.7％) and unknown reasons (4 cases,3.4％).Conclusion Binocular diplopia is a complicated syndrome.Multiple methods should be combined to identify the latent causes and find better treatments. Key words: Diplopia; Strabismus ; Adult

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