Clinical analysis of 62 cases of liver transplantation from donation after citizen death

Abstract

Objective To provide evidence for the liver transplantation from donation after citizen death by analyzing the procedure and effect of liver transplantation from donation after citizen's death. Methods The receptors' clinical data, donor maintenance, organ procurement, the recptors' perioperative and prognosis of sixty-two recipients undergoing liver transplantation from donation after citizen's death were retrospectively analyzed from Oct 2008 to Dec 2015 in Zhongshan Hospital affiliated to Sun Yat-sen University. Results All the 62 cases were conformed to meet the standard of donation after brain death plus cardiac death (DBCD). Liver graft and harvesting was procured according to technological process standard, including 15 donors treated with extracoporeal membrane oxygenation (ECMO). The warm ischemia time of donation was 0-30 (16.2±6.5) min, and the cold time of donation was 190-680 (347±39) min. All recipients were successfully implanted the donor liver, with no primary malfunction or rejection. 1 recipient died of multiple arterial thrombosis in perioperative period, and 3 from tumor recurrence and metastasis. 3 recipients suffered from biliary complication, including 1 bile leakage recovering after drainage, 2 biliary stricture relieving after stenting biliary stent. Conclusion Liver transplantation from donation after citizen death can be clinically satisfactory with making reasonable procedure of ECMO, reinforcing the management of organ procurement, and reducing the warm and cold ischemic time. Key words: Tissue and organ harvesting; Liver transplantation; Extracoporeal membrane oxygenation; Prognosis