Abstract
Objective To investigate the clinical data of Mycoplasma pneumoniae pneumonia(MPP) complicated with embolism in children, and to improve the understanding of the clinical features, diagnosis and treatment of the disease. Methods Six cases of MPP complicated with embolization, who were treated at Nanjing Children's Hospital Affiliated to Nanjing Medical University from January 2010 to June 2015, were analyzed retrospectively. Results The ages of 6 cases ranged from 3 years and 3 months old to 13 years and 10 months old, and 3 cases were boys, 3 cases were girls.All of 6 patients had high fever, positive anti-Mycoplasma IgM antibody (≥1︰160) and sputum fluorescence quantitative-Mycoplasma pneumonia (FQ-MP DNA), and all the chest imaging was consistent with pneumonia.Among 6 patients, 4 cases complicated with liver function damage, 4 cases had D-dimer rise, 5 cases of erythrocyte sedimentation rate increased at different degree, while pleural effusion or pleuritis was found in 5 cases.The region of embo-lism in the cases included left renal artery in 1 case, the left popliteal artery in 1 case, the right middle cerebral artery embolism combined with cerebral infarction in 1 case, the right subclavian vein embolism combined with right upper extremity embolism in 1 case, the basilar artery and bilateral posterior cerebral artery embolism combined with cerebral infarction in 1 case, and the other case involved the right pulmonary embolism.One case received thrombus dislodgment operation, and all of 6 cases were given the treatment including anti-infection, anticoagulation and low dose of glucocorticoid the-rapy, among whom 1 case died of cerebral hernia, and the other 5 cases improved. Conclusions MPP is often complicated with hypercoagulative state and potentialized to thrombosis, and thrombus may occur in vessels of whole body organs, and cerebral infarction had poor prognosis.Consequently, doctors should be aware of the potential risk factors for thrombosis.Early diagnosis and prompt anticoagulation and thrombolytic therapy could reduce mortality and disability rate. Key words: Mycoplasma pneumoniae pneumonia; Embolism; Thrombus; Child
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