Clinical analysis of 512 cases of ectopic pregnancy

Abstract

Objective To investigate the early diagnosis of ectopic pregnancy ( EP) , as well as use conservative treatment of EP. Methods The clinical datas of five hundred and twelve patients with EP admitted from Jan. 2003 to Dec. 2008 were analyzed retrospectively, and 200 of them attemped to conceive again with fertility after radical by different treatment for tubal pregnancy were compared. Results From 2003 to 2008, the incidence of EP in this region increased one times. Positive serum β-hCG test was 100% , the absence of intrauterine gestational sac was 93.9% , the success rate of expectant management was 85.4% , the curative rate of single agent methotrexate therapy was 92. 3% ,the success rate of conservative surgery was 89. 5% .there was 56. 7% , 65. 0% and 46. 7% respectively, the two - year cumlative rate that next pregnancy was intrauterine, the rate of reectopic pregnancy was 13.3% , 7.5% and 11.3% , respectively. Conclusions Improved pivotal technology and the rising incidence of acute and chronic salpingirtis, related to chlamydia trachomatis is primary factors of this increased incidence. The diagnosis of early EP may be confirmed by serum (3 - HCG≥ 2000 mlu/ml and the absence of intrauterine gestational sac. Single - agent im MTX chemotherapy is a most effective and most applies to conservative treatment, within sight will become the standardized therapy of early EP. Key words: Early ectopic pregnancy; Diagnosis and treatment