Clinical analysis of 102 cases of proliferative diabetic retinopathy with surgical treatment

Abstract

Objective To observe the surgical effect of vitrectomy for treating PDR and investigate the factors which influence the surgery. Methods The clinical data of 117 eyes (102 patients)who underwent vitrectomy by the same surgeon in our hospital were retrospectively studied from March,2008 to December,2009. Results Thirty-six eyes (85.71％) in PDR Ⅳ group,27 eyes (69.23％) in PDR Ⅴ group and 19 eyes (52.78％) in PDR Ⅵ group gained improvements in visual acuity after surgery.According to the duration of vitreous hemorrhage in PDR Ⅳ group,the postoperative visual acuity improvement rate of less than 2 months group was higher than that of 2-3months group (x2=4.621,P =0.032).There was no significant difference between 2-3 months group and more than 3 months group (x2=0,P =1.000).The total eyes with anatomically retinal attachment after one surgery were 112 (95.73％),including 41 eyes (97.62％) in PDR Ⅳ group,38 eyes (97.44％) in PDR Ⅴ group and 33 eyes (91.67％) in PDR Ⅵ group.Recurrent vitreous hemorrhage,The 9 eyes (17.31％) in irrigation solution group,4 eyes (13.33％) in C3F8 group and 6 eyes (17.14％) in silicon oil group presented recurrent vitreous hemorrhage.After vitrectomy,the distinction had no statistical significance (x2=0.251,P =0.882).The 3 eyes (6.52％) in preoperative PRP group and 16 eyes (22.54％) in non-preoperative PRP group encountered postoperative vitreous hemorrhage respectively,the distinction had statistical significance (x2=4.151,P=0.042). Conclusions The visual acuities of PDR patients can be well improved by pars plana vitrectomy.To master the appro priate opportunity of surgery is crucial for good prognosis. Key words: Proliferative diabetic retinopathy; Vitrectomy; Hemorrhage