Clinic characters analysis of 52 cases with sinus fungus ball disease

Abstract

Objective:To explore the clinic characters and the associated factors for the onset of the sinus fungus ball disease. Method:Analyze 52 cases who have received surgery with sinus fungus ball disease retrospectively. The effect factors of age, sex, occupation, the side of the lesion, involving sinus group number, accompany with merger polyps or not, presence of nasal septum deviation, vesicular middle turbinate, paradoxical middle turbinate, infraorbital cells，routine blood leukocyte classification, serum specific IgE, pathogenic fungi species have all been taken into consideration for statistical analysis. Result:In 52 cases of sinus fungus ball disease, 36 cases only suffered in maxillary sinus, 1 case only suffered in ethmoid sinus, 4 cases only suffered in sphenoid sinus, 7 cases suffered from two sinus lesions with the combination of maxillary sinus and ethmoid sinus in all, 4 cases fuffered from three sinus lesions with the combination of maxillary sinus, ethmoid sinus and sphenoid sinus in 2 cases, maxillary sinus, ethmoid sinus and frontal sinus in 2 cases. 26 cases have the lesion on left side,17 cases on the right side, 8 cases on both sides. Aspergillus is the main pathogenic fungus for sinus fungus ball. Maxillary sinus is the most susceptible single sinus for sinus fungus ball. Nasal polyps is commonly seen in multiple sinuses fungus ball(P<0.01). Single sphenoid sinus fungus ball is more commonly seen in the patients with diabetes mellitus(P<0.01). Lesion side of sinus fungus ball has nothing to do with the nasal anatomy abnormalities of nasal septum deviation, vesicular middle turbinate, paradoxical middle turbinate, infraorbital cells. Conclusion:The present study indicates that maxillary sinus fungus ball is the most common type for sinus fungus ball. Aspergillus is the main pathogenic fungus for sinus fungus ball. Nasal polyps is more involved in multiple sinuses fungus ball,Single sphenoid sinus fungus ball is more commonly seen in the patients with diabetes mellitus. Lesion side of sinus fungus ball has none relationship with common nasal anatomy abnormalities.