Abstract

Objective — to improve the results of treatment of patients with intramedullary ependymomas. Materials and methods. The results of treatment of 29 patients (14 men and 15 women aged 18 to 64 years) with intramedullary ependymomas operated on at the Romodanov Institute of Neurosurgery of the National Academy of Medical Sciences of Ukraine were analysed. All patients who were scheduled for surgery underwent magnetic resonance imaging (MRI) with paramagnetic contrast agent. The preoperative and postoperative neurological status was assessed using the modified McCormick scale. Results. Microsurgical technique for removal of spinal cord tumors was used in all 29 observations. According to the volume of tumor removal, operations with total (12 observations), subtotal (9 observations) and partial (8 observations) removal were distinguished. Removal of at least 95 % of the tumor volume, which was confirmed by visualization with a microscope during surgery and early postoperative MRI, was considered total. At the time of discharge from the hospital, in 11 patients (37.9 %) the neurological condition improved compared to the preoperative period, in 13 (44.8 %) it remained unchanged, and in 5 (17.2 %) there was an increase in neurological symptoms. 12 patients were examined 12—36 months after the operation. Improvement compared to the preoperative period was found in 10 patients, and no changes in 2. There were no cases of worsening of neurological symptoms during this period. MRI performed before discharge from the hospital showed almost normal spinal cord diameter in the area of surgical procedures, and MRI performed ≥ 3 months after total tumour removal showed atrophic changes in the spinal cord with ependymoma localisation at the thoracic level. Conclusions. Intramedullary ependymomas can be totally removed, and surgical intervention must be carried out immediately after the diagnosis before the appearance of signs of increasing neurological deficit. Thanks to the use of microsurgical techniques and an intraoperative microscope, it is possible to achieve positive functional results during the total removal of intramedullary tumors.

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