Abstract
A 16-year-old boy received IV infusion of clindamycin 0.6 g twice daily after incision and drainage of anal abscess. Three days after initiation of clindamycin treatment, the boy developed palpitations and chest tightness. The ECG examination showed ST-segment depression and T wave inversion inⅡ, Ⅲ, and aVF leads. After excluding viral myocarditis, congenital heart disease, rheumatic myocarditis, the electrocardiographic ST-T changes in the patient was considered to be related to clindamycin treatment. Cardiac enzymes, ECG, and blood electrolyte changes were monitored and the patient's palpitations and chest tightness disappeared after 2 days of symptomatic treatments. After 5 days of treatment, the electrocardiographic ST-T changes in the patient disappeared. At 1 month of follow-up, the boy's symptoms did not recur and ECG examination showed normal findings. Key words: Clindamycin; Electrocardiography; Palpitation
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