Click and Click‐Inspired Chemistry for the Design of Sequence‐Controlled Polymers

Abstract

In the previous decade, “click” chemistry and similarly efficient click-inspired reactions along with sequence-defined and sequence-controlled structures were introduced into the field of macromolecular chemistry. The introduction of these two important topics has already made a great impact and has enabled the synthesis of highly functionalized and complex oligomeric and polymeric structures, offering the prospect of many exciting further developments and applications in the near future. In this chapter, the fruitful combination of these two topics for the preparation of sequence-controlled oligomeric and macromolecular structures will be highlighted. This chapter is divided into three sections according to the click-(inspired) reaction that has been applied. Copper-catalyzed azide–alkyne cycloaddition, thiol–X and related thiolactone-based reactions, and finally Diels–Alder chemistry-based routes are outlined, respectively.