Abstract
This study shows the possibility of anchoring antibody fragments on to carrier surfaces with biocompatible coatings. Cleavage of whole antibody molecules into two fragments is performed with immobilized dihydrolipoamide. The proof of successful coating and immobilization of antibody fragments is shown by use of fluorescence microscopy. The biocompatibility of a poly(ethylene glycol) coating, on 316L stainless steel as carrier, was shown in cell culture with Caco-2 cells. Immobilization of antibody fragments can serve another purpose—as a suitable specific binding site for nano or microparticulate drug-delivery systems.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Paper version not known
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Monatshefte für Chemie und verwandte Teile anderer Wissenschaften
Paper Title
Journal
Date
