Abstract
Homologous and autologous rat erythrocytes, human erythrocytes as well as glutaraldehydetreated and hemolysed homologous red blood cells suspended in an isotonic, buffered saline, free of immunoglobulins were perfused through the isolated rat liver. The mononuclear phagocyte system of the liver (mainly Kupffer cells) was able to recognize damaged rat and heterologous human erythrocytes and to sequester them by a direct membrane-erythrocyte mechanism. Hemoglobin and homologous and autologous rat erythrocytes were not sequestered or only to a minor extent. High sequestration rates are reflected by an increased energy demand with subsequent increase of the lactate-pyruvate and beta-hydroxybutyrate-acetoacetate-quotient.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
